Mobilization of peripheral blood progenitor cells for allogeneic transplantation

被引：0
|
作者：
Teshima, T [1 ]
Harada, M [1 ]
机构：
[1] OKAYAMA UNIV, SCH MED, DEPT MED 2, OKAYAMA 700, JAPAN
来源：
CYTOKINES CELLULAR & MOLECULAR THERAPY | 1997年 / 3卷 / 02期
关键词：
peripheral blood stem progenitor cells; mobilization; G-CSF; CD34(+) cells; allotransplantation;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Allogeneic transplantation of peripheral blood stem/progenitor cells (PBSC/PBPC) has been increasingly used as an alternative to allogeneic bone marrow transplantation. To mobilize and collect a sufficient number of PBSC/PBPC for engraftment after allotransplantation, granulocyte colony-stimulating factor (G-CSF) has keen preferentially used. The mobilization protocol, however, has not been fully established. In this review, dose and schedule of G-CSF administration, characteristics of G-CSF-mobilized PBPC products, cytokines other than G-CSF for PBSC/PBPC mobilization, and safety of the PBSC/PBPC donors are discussed for clinical application of allogeneic PBSC/PBPC transplantation.
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收藏
页码：101 / 114
页数：14
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