Oxidative Decarboxylation of 2-Aryl Carboxylic Acids Using (Diacetoxyiodo)benzene for Preparation of Aryl Aldehydes, Ketones, and Nitriles

被引：22
|
作者：
Telvekar, Vikas N. [1 ]
Sasane, Kulbhushan A. [1 ]
机构：
[1] Inst Chem Technol, Dept Pharmaceut Sci & Technol, Bombay 400019, Maharashtra, India
来源：
SYNLETT | 2010年 / 18期
关键词：
(diacetoxyiodo)benzene; decarboxylation; aldehydes; ketones; nitriles; AMINO-ACIDS; HIGHLY EFFICIENT; ALPHA-AMINO; PERIODATE;
D O I：
10.1055/s-0030-1258812
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel synthetic application of the hypervalent iodine reagent, (diacetoxyiodo)benzene, and catalytic amount of sodium azide in acetonitrile for oxidative decarboxylation of 2-aryl carboxylic acids into corresponding aldehydes, ketones, and nitriles at room temperature is described. The advantages of this protocol are shorter reaction times and mild reaction conditions to obtain moderate to good yields
引用
收藏
页码：2778 / 2780
页数：3
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