Novel synthesis of fosphenytoin: Anti-convulsant prodrug

被引:5
|
作者
Elati, Chandrashekar R.
Gangula, Srinivas
Naredla, Anitha
Ashok, S. [2 ]
Bhattacharya, Apurba
Bandichhor, Rakeshwarar [1 ]
机构
[1] Dr Reddys Labs Ltd, IPD, R&D, Qutubullapur 500073, AP, India
[2] Osmania Univ, Dept Chem, Hyderabad 500007, Andhra Pradesh, India
关键词
anti-convulsant; hemiaminol; imidate ester;
D O I
10.1080/00397910802005281
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A simple, new synthesis of fosphenytoin sodium 1, a prodrug, via imidate ester and employing mild reaction conditions is described.
引用
收藏
页码:2950 / 2957
页数:8
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