Bacteria fight back against Toll-like receptors

被引：10
|
作者：
O'Neill, Luke A. J. [1 ]
机构：
[1] Trinity Coll Dublin, Sch Biochem & Immunol, Dublin 2, Ireland
来源：
NATURE MEDICINE | 2008年 / 14卷 / 04期
关键词：
D O I：
10.1038/nm0408-370
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A strain of Escherichia coli that causes urinary tract infections seems to take hold in the body by interfering with signaling through Toll-like receptors (TLRs). The mechanism involves a secreted bacterial protein that is taken up by cells and clogs up the TLR signaling mechanism ( pages 399-406).
引用
收藏
页码：370 / 372
页数：4
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