Identification of an inverse agonist at the ADP receptor P2Y12

被引:0
|
作者
Schmidt, Philipp [1 ]
Coester, Maxi [1 ]
Simon, Kay-Uwe [1 ]
Schoeneberg, Torsten [1 ]
机构
[1] Univ Leipzig, Fac Med, Inst Biochem, D-04103 Leipzig, Germany
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:150 / 150
页数:1
相关论文
共 50 条
  • [1] Identification of a potent inverse agonist at a constitutively active mutant of human P2Y12 receptor
    Ding, ZG
    Kim, S
    Kunapuli, SP
    MOLECULAR PHARMACOLOGY, 2006, 69 (01) : 338 - 345
  • [2] Identification of Determinants Required for Agonistic and Inverse Agonistic Ligand Properties at the ADP Receptor P2Y12
    Schmidt, Philipp
    Ritscher, Lars
    Dong, Elizabeth N.
    Hermsdorf, Thomas
    Coester, Maxi
    Wittkopf, Doreen
    Meiler, Jens
    Schoeneberg, Torsten
    MOLECULAR PHARMACOLOGY, 2013, 83 (01) : 256 - 266
  • [3] Identification of a potent inverse agonist at a constitutively active mutant of human P2Y12 receptor.
    Ding, ZR
    Kim, SC
    Kunapuli, SP
    BLOOD, 2005, 106 (11) : 65B - 65B
  • [4] The structural landscape of the ADP receptor P2Y12
    Schoeneberg, T.
    PURINERGIC SIGNALLING, 2012, 8 (01) : 118 - 118
  • [5] Prasugrel: A Novel Platelet ADP P2Y12 Receptor Antagonist
    Wilson, William
    Gurvitch, Ronen
    Ajani, Andrew E.
    CARDIOVASCULAR THERAPEUTICS, 2009, 27 (03) : 194 - 198
  • [6] The structural and functional landscape of the human ADP receptor P2Y12
    Coester, Maxi
    Simon, Kay-Uwe
    Thor, Doreen
    Schoeneberg, Torsten
    PURINERGIC SIGNALLING, 2010, 6 (01) : 76 - 77
  • [7] P2Y12, a new platelet ADP receptor, target of clopidogrel
    Savi, P
    Labouret, C
    Delesque, N
    Guette, F
    Lupker, J
    Herbert, JM
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2001, 283 (02) : 379 - 383
  • [8] The structural and functional landscape of the human ADP receptor P2Y12
    Coester, Maxi
    Wittkopf, Doreen
    Simon, Kay-Uwe
    Thor, Doreen
    Kreuchwig, Annika
    Kleinau, Gunnar
    Krause, Gerd
    Schoeneberg, Torsten
    PURINERGIC SIGNALLING, 2012, 8 (01) : 151 - 151
  • [9] Agonist-bound structure of the human P2Y12 receptor
    Jin Zhang
    Kaihua Zhang
    Zhan-Guo Gao
    Silvia Paoletta
    Dandan Zhang
    Gye Won Han
    Tingting Li
    Limin Ma
    Wenru Zhang
    Christa E. Müller
    Huaiyu Yang
    Hualiang Jiang
    Vadim Cherezov
    Vsevolod Katritch
    Kenneth A. Jacobson
    Raymond C. Stevens
    Beili Wu
    Qiang Zhao
    Nature, 2014, 509 : 119 - 122
  • [10] Agonist-bound structure of the human P2Y12 receptor
    Zhang, Jin
    Zhang, Kaihua
    Gao, Zhan-Guo
    Paoletta, Silvia
    Zhang, Dandan
    Han, Gye Won
    Li, Tingting
    Ma, Limin
    Zhang, Wenru
    Mueller, Christa E.
    Yang, Huaiyu
    Jiang, Hualiang
    Cherezov, Vadim
    Katritch, Vsevolod
    Jacobson, Kenneth A.
    Stevens, Raymond C.
    Wu, Beili
    Zhao, Qiang
    NATURE, 2014, 509 (7498) : 119 - 122