Potent HIV Neutralizing Antibodies Elicited by BG505 SOSIP Trimer Immunization in Rhesus Macaques as a Starting Point for Iterative Vaccine Design

被引:0
|
作者
van Gils, Marit [1 ]
van Schooten, Jelle [1 ]
Cottrell, Christopher [2 ]
Ozorowski, Gabriel [2 ]
Morpurgo, Robert [1 ]
Sok, Devin [2 ]
Burton, Dennis [2 ]
Moore, John [3 ]
Ward, Andrew [2 ]
Sanders, Rogier [1 ]
机构
[1] Univ Amsterdam, Acad Med Ctr, NL-1012 WX Amsterdam, Netherlands
[2] Scripps Res Inst, San Diego, CA USA
[3] Weill Cornell Med Coll, New York, NY USA
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
OA08.01
引用
收藏
页码:57 / 57
页数:1
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    van Schooten, Jelle
    van Haaren, Marlies M.
    Cottrell, Christopher
    Sok, Devin
    Burton, Dennis R.
    Havenar-Daughton, Colin
    Crotty, Shane
    Ward, Andrew B.
    Shaw, George M.
    Sanders, Rogier W.
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    [J]. AIDS RESEARCH AND HUMAN RETROVIRUSES, 2018, 34 : 334 - 334
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    Klasse, P. J.
    Ketas, Thomas J.
    Cottrell, Christopher A.
    Ozorowski, Gabriel
    Debnath, Gargi
    Camara, Diawoye
    Francomano, Erik
    Pugach, Pavel
    Ringe, Rajesh P.
    LaBranche, Celia C.
    van Gils, Marit J.
    Bricault, Christine A.
    Barouch, Dan H.
    Crotty, Shane
    Silvestri, Guido
    Kasturi, Sudhir
    Pulendran, Bali
    Wilson, Ian A.
    Montefiori, David C.
    Sanders, Rogier W.
    Ward, Andrew B.
    Moore, John P.
    [J]. PLOS PATHOGENS, 2018, 14 (02)
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    Nelson, A.
    Dennis, M.
    LaBranche, C. C.
    Eudailey, J.
    Montefiori, D. C.
    Sanders, R. W.
    Moore, J. P.
    Fouda, G.
    Van Rompay, K. K.
    De Paris, K.
    Permar, S. R.
    [J]. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2021, 24
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    Bianchi, Matteo
    Turner, Hannah L.
    Nogal, Bartek
    Cottrell, Christopher A.
    Oyen, David
    Pauthner, Matthias
    Bastidas, Raiza
    Nedellec, Rebecca
    Mccoy, Laura E.
    Wilson, Ian A.
    Burton, Dennis R.
    Ward, Andrew B.
    Hangartner, Lars
    [J]. IMMUNITY, 2018, 49 (02) : 288 - +
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    Charles, Tysheena P.
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    Legere, Traci
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    Bollimpelli, Venkata S.
    Ward, Andrew
    Hunter, Eric
    Amara, Rama R.
    Pulendran, Bali
    Derdeyn, Cynthia A.
    [J]. JOURNAL OF MEDICAL PRIMATOLOGY, 2020, 49 (05) : 249 - 249
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    van Gils, Marit J.
    King, C. Richter
    Wilson, Ian A.
    Ward, Andrew B.
    Klasse, P. J.
    Moore, John P.
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    Nelson, A. N.
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    Moore, J. P.
    Fouda, G. G.
    Van Rompay, K. K. A.
    De Paris, K.
    Permar, S. R.
    [J]. JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2020, 23 : 168 - 168
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