Use of antidepressant medications during pregnancy: a multisite study

被引：308

作者：

Andrade, Susan E. ^{[1
,2
,3
]}

Raebel, Marsha A. ^{[3
,4
]}

Brown, Jeffrey ^{[3
,5
,6
]}

Lane, Kimberly ^{[3
,5
,6
]}

Livingston, James ^{[3
,5
,6
]}

Boudreau, Denise ^{[3
,7
]}

Rolnick, Sharon J. ^{[3
,8
]}

Roblin, Douglas ^{[3
,9
]}

Smith, David H. ^{[3
,10
]}

Willy, Mary E. ^{[11
]}

Staffa, Judy A. ^{[11
]}

Platt, Richard ^{[3
]}

机构：

[1] Univ Massachusetts, Sch Med, Fallon Fdn, Meyers Primary Care Inst, Worcester, MA 01605 USA

[2] Fallon Commun Hlth Plan, Worcester, MA USA

[3] Ctr Educ & Res Therapeut, HMO Res Network, Denver, CO USA

[4] Kaiser Permanente Colorado, Denver, CO USA

[5] Harvard Univ, Sch Med, Dept Ambulatory Care & Prevent, Boston, MA 02115 USA

[6] Harvard Pilgrim Hlth Care, Boston, MA USA

[7] Grp Hlth Cooperat Puget Sound, Ctr Hlth Studies, Seattle, WA 98101 USA

[8] Hlth Partners Res Fdn, Minneapolis, MN USA

[9] Kaiser Permanente Georgia, Atlanta, GA USA

[10] Kaiser Permanente NW, Portland, OR USA

[11] US FDA, Ctr Drug Evaluat & Res, Off Surveillance & Epidemiol, Silver Spring, MD USA

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 2008年 / 198卷 / 02期

关键词：

antidepressant drugs; pregnancy;

D O I：

10.1016/j.ajog.2007.07.036

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

OBJECTIVE: This study was undertaken to provide information on the prevalence of use of antidepressant drugs among pregnant women in the United States. STUDY DESIGN: A retrospective study was conducted using the automated databases of 7 health plans. Women who delivered an infant in a hospital were identified. Antidepressant drug use was evaluated assuming a gestational duration of 270 days. RESULTS: Among the 118,935 deliveries occurring from 2001-2005, 6.6% of women were dispensed an antidepressant during pregnancy. Antidepressant drug use increased from 2.0% in 1996 to 7.6% of deliveries in 2004 and 2005. Selective serotonin re-uptake inhibitor use increased from 1.5% in 1996 to 6.4% in 2004 and 6.2% in 2005. CONCLUSION: Our finding that nearly 8% of pregnant women were prescribed antidepressants drugs during the years 2004 and 2005 highlights the importance of understanding the effects of these medications on the developing fetus and on the pregnant woman.

引用

页码：194.e1 / 194.e5

页数：5

共 50 条

[1] Safety of antidepressant medications during pregnancy - Reply
Wisner, KL
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2000, 283 (09): : 1139 - 1139
[2] The Use of Antidepressant Medications During Pregnancy and the Risk of Neonatal Seizures A Systematic Review
Uguz, Faruk
[J]. JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 2019, 39 (05) : 479 - 484
[3] Antidepressant medications in pregnancy
Huntington, J
Zantop, V
[J]. AMERICAN FAMILY PHYSICIAN, 2004, 70 (11) : 2195 - 2196
[4] Antidepressant use during pregnancy
Boksa, P
[J]. JOURNAL OF PSYCHIATRY & NEUROSCIENCE, 2001, 26 (01): : 17 - 19
[5] Antidepressant use during pregnancy
Kayyali, A
Cain, JE
[J]. AMERICAN JOURNAL OF NURSING, 2006, 106 (05) : 64L - +
[6] Antidepressant Use During Pregnancy
Patel, Beena N.
Beste, Janalynn
Blackwell, Jean C.
[J]. AMERICAN FAMILY PHYSICIAN, 2011, 83 (10) : 1211 - +
[7] Maternal use of cough medications during early pregnancy and selected birth defects: a US multisite, case-control study
Cao, Yanyan
Rhoads, Anthony
Burns, Trudy
Carnahan, Ryan M.
Conway, Kristin M.
Werler, Martha M.
Mitchell, Allen
Romitti, Paul
[J]. BMJ OPEN, 2021, 11 (12):
[8] Maternal Use of Specific Antidepressant Medications During Early Pregnancy and the Risk of Selected Birth Defects
Anderson, Kayla N.
Lind, Jennifer N.
Simeone, Regina M.
Bobo, William V.
Mitchell, Allen A.
Riehle-Colarusso, Tiffany
Polen, Kara N.
Reefhuis, Jennita
[J]. JAMA PSYCHIATRY, 2020, 77 (12) : 1246 - 1255
[9] Antidepressant use (during pregnancy) and miscarriage
Berard, Anick
Nakhai-Pour, Hamid Reza
Broy, Perrine
[J]. CANADIAN MEDICAL ASSOCIATION JOURNAL, 2010, 182 (10) : 1079 - 1079
[10] Antidepressant Use During Pregnancy and Asthma in the Offspring
Liu, Xiaoqin
Olsen, Jorn
Pedersen, Lars Henning
Agerbo, Esben
Yuan, Wei
Li, Jiong
[J]. PEDIATRICS, 2015, 135 (04) : E911 - E917

← 1 2 3 4 5 →