Noncoding RNA as Diagnostic and Prognostic Biomarkers in Cerebrovascular Disease

被引：11
|
作者：
Weng, Ruiyuan [1 ,2 ,3 ,4 ]
Jiang, Zhiwen [1 ,2 ,3 ,4 ]
Gu, Yuxiang [1 ,2 ,3 ,4 ]
机构：
[1] Fudan Univ, Huashan Hosp, Shanghai Med Coll, Dept Neurosurg, Shanghai, Peoples R China
[2] Fudan Univ, Neurosurg Inst, Shanghai, Peoples R China
[3] Shanghai Clin Med Ctr Neurosurg, Shanghai, Peoples R China
[4] Shanghai Key Lab Brain Funct & Restorat & Neural, Shanghai, Peoples R China
来源：
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY | 2022年 / 2022卷
基金：
中国国家自然科学基金;
关键词：
FOCAL CEREBRAL-ISCHEMIA; CEREBROSPINAL-FLUID; CIRCULATING MICRORNAS; ALTERED EXPRESSION; MOYAMOYA-DISEASE; DOWN-REGULATION; SUBARACHNOID HEMORRHAGE; NEURONAL APOPTOSIS; THERAPEUTIC TARGET; REPERFUSION INJURY;
D O I：
10.1155/2022/8149701
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Noncoding RNAs (ncRNAs), such as microRNAs, long noncoding RNAs, and circular RNAs, play an important role in the pathophysiology of cerebrovascular diseases (CVDs). They are effectively detectable in body fluids, potentially suggesting new biomarkers for the early detection and prognosis of CVDs. In this review, the physiological functions of circulating ncRNAs and their potential role as diagnostic and prognostic markers in patients with cerebrovascular diseases are discussed, especially in acute ischemic stroke, subarachnoid hemorrhage, and moyamoya disease.
引用
收藏
页数：12
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