Secondary nephropathic amyloidosis in cystic fibrosis

被引:3
|
作者
Guillot, M
Drut-Desombre, B
Amiour, M
Aljazayri, Z
Eckart, P
Dominique, S
Grateau, G
机构
[1] Ctr Hosp Gen, Serv Pediat, F-14107 Lisieux, France
[2] Ctr Hosp Gen, Ctr Soins Mucoviscidose, F-14107 Lisieux, France
[3] CHU, Serv Pneumol, F-76031 Rouen, France
[4] Ctr Hosp Hotel Dieu, Serv Med Interne, F-75181 Paris 04, France
来源
ARCHIVES DE PEDIATRIE | 1998年 / 5卷 / 08期
关键词
amyloidosis; cystic fibrosis; kidney failure; chronic; adult;
D O I
10.1016/S0929-693X(98)80133-4
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Background. - Due to the improvement in cystic fibrosis management, life expectancy has risen; on the other hand, longer survival has led to new complications, including secondary renal amyloidosis, which has been so far very uncommonly reported. Case reports. - Secondary nephropathic amyloidosis was seen in two 25-year and 22-year-old adults with cystic fibrosis. Both had developed recurrent pulmonary infections due to Pseudomonas aeruginosa over several years. One patient died after 2 years of progressive kidney failure. Conclusion. - Severe renal insufficiency due to secondary amyloidosis may complicate the course of cystic fibrosis and become the main prognosis factor in adults. (C) 1998, Elsevier, Paris.
引用
收藏
页码:884 / 886
页数:3
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