Management of hepatocellular carcinoma: An overview of major findings from meta-analyses

被引:54
|
作者
Qi, Xingshun [1 ,2 ,3 ]
Zhao, Yan [3 ,4 ]
Li, Hongyu [1 ,2 ]
Guo, Xiaozhong [1 ,2 ]
Han, Guohong [3 ]
机构
[1] Shenyang Mil Area, Gen Hosp, Dept Gastroenterol, Shenyang 110840, Peoples R China
[2] Shenyang Mil Area, Gen Hosp, Meta Anal Study Interest Grp, Shenyang 110840, Peoples R China
[3] Fourth Mil Med Univ, Xijing Hosp Digest Dis, Dept Liver Dis & Digest Intervent Radiol, Xian 710032, Peoples R China
[4] Xi An Jiao Tong Univ, Affiliated Hosp 1, Coll Med, Dept Gastroenterol, Xian 710000, Peoples R China
关键词
hepatocellular carcinoma; treatment; management; meta-analysis; systematic review; TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION; ADJUVANT INTERFERON THERAPY; PERCUTANEOUS RADIOFREQUENCY ABLATION; SALVAGE LIVER-TRANSPLANTATION; TRADITIONAL CHINESE MEDICINE; LONG-TERM OUTCOMES; TRANSARTERIAL CHEMOEMBOLIZATION; CURATIVE TREATMENT; HEPATIC RESECTION; SURGICAL RESECTION;
D O I
10.18632/oncotarget.9157
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
This paper aims to systematically review the major findings from meta-analyses comparing different treatment options for hepatocellular carcinoma (HCC). A total of 153 relevant papers were searched via the PubMed, EMBASE, and Cochrane library databases. They were classified according to the mainstay treatment modalities (i.e., liver transplantation, surgical resection, radiofrequency ablation, transarterial embolization or chemoembolization, sorafenib, and others). The primary outcome data, such as overall survival, diseases-free survival or recurrence-free survival, progression-free survival, and safety, were summarized. The recommendations and uncertainties regarding the treatment of HCC were also proposed.
引用
收藏
页码:34703 / 34751
页数:49
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