Gastrointestinal colonization by Candida albicans mutant strains in antibiotic-treated mice

被引:43
|
作者
Wiesner, SM
Jechorek, RP
Garni, RM
Bendel, CM
Wells, CL
机构
[1] Univ Minnesota, Dept Lab Med & Pathol, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Dept Pediat, Minneapolis, MN 55455 USA
[3] Univ Minnesota, Dept Surg, Minneapolis, MN 55455 USA
关键词
D O I
10.1128/CDLI.8.1.192-195.2001
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Antibiotic-treated mice orally inoculated with one of three Candida albicans strains (including two mutant strains) or indigenous Candida pelliculosa showed levels of candidal gastrointestinal colonization that were strain specific. However, regardless of strain, the numbers of viable candida were intermediate to high in the stomach, were consistently lowest in the upper small intestine, and increased progressively down the intestinal tract.
引用
收藏
页码:192 / 195
页数:4
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