Persons with virological failure (VF) on an initial boosted-PI regimen infrequently possess low-level variants with major PI drug resistance mutations (DRMs) by ultra-deep sequencing (UDS)

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作者
Lataillade, M. [1 ,2 ,3 ]
Chiarella, J. [1 ,2 ]
Yang, R. [3 ]
Degrosky, M. [3 ]
Seekins, D. [3 ]
Uy, J. [3 ]
McGrath, D. [3 ]
Simen, B. [4 ]
Egholm, M. [4 ]
Kozal, M. J. [1 ,2 ]
机构
[1] Yale Univ Sch Med, New Haven, CT USA
[2] Vet Affairs Healthcare Syst, New Haven, CT USA
[3] Bristol Myers Squibb Co, Res & Dev, Wallingford, CT 06492 USA
[4] 454 Life Sci Roche Co, Branford, CT USA
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中图分类号
R51 [传染病];
学科分类号
100401 ;
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页码:A128 / A128
页数:1
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  • [1] Virologic Failures on Initial Boosted-PI Regimen Infrequently Possess Low-Level Variants with Major PI Resistance Mutations by Ultra-Deep Sequencing
    Lataillade, Max
    Chiarella, Jennifer
    Yang, Rong
    DeGrosky, Michelle
    Uy, Jonathan
    Seekins, Daniel
    Simen, Birgitte
    St John, Elizabeth
    Moreno, Elizabeth
    Kozal, Michael
    PLOS ONE, 2012, 7 (02):