High-resolution computed tomography manifestations of COVID-19 infections in patients of different ages

Purpose: We aimed to compare chest HRCT lung signs identified in scans of differently aged patients with COVID-19 infections. Methods: Case data of patients diagnosed with COVID-19 infection in Hangzhou City, Zhejiang Province in China were collected, and chest HRCT signs of infected patients in four age groups ( < 18 years, 18-44 years, 45-59 years, >= 60 years) were compared. Results: Small patchy, ground-glass opacity (GGO), and consolidations were the main HRCT signs in 98 patients with confirmed COVID-19 infections. Patients aged 45-59 years and aged >= 60 years had more bilateral lung, lung lobe, and lung field involvement, and greater lesion numbers than patients < 18 years. GGO accompanied with the interlobular septa thickening or a crazy-paving pattern, consolidation, and air bronchogram sign were more common in patients aged 45-59 years, and >= 60 years, than in those aged < 18 years, and aged 18-44 years. Conclusions: Chest HRCT manifestations in patients with COVID-19 are related to patient's age, and HRCT signs may be milder in younger patients.