SYNTHESIS OF N-HETEROCYCLIC CARBENE LIGANDS FOR SITE-SELECTIVE C-H ALKYLATION BY COOPERATIVE NICKEL/ALUMINUM CATALYSIS

被引：5

作者：

Okumura, Shogo ^{[1
]}

Ebara, Tomohiro ^{[1
]}

Semba, Kazuhiko ^{[1
]}

Nakao, Yoshiaki ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Mat Chem, Nishikyo Ku, Kyoto 6158510, Japan

来源：

HETEROCYCLES | 2019年 / 99卷 / 02期

关键词：

D O I：

10.3987/COM-18-S(F)84

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report synthesis of N-heterocyclic carbenes (NHCs), N,N'-bis{2,6-bis(3,5-dialkylphenyl)methy-4-methoxyphenyl}imidazol-2-ylidenes {alkyl = ethyl (L2) or n-propyl (L3)} and their applications to nickel-catalyzed C-H alkylation reactions of arenes. They showed site-selectivities and/or yields higher than NHCs used previously for the reactions.

引用

页码：1128 / 1144

页数：17

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