The Association between Chronic Heroin Smoking and Chronic Obstructive Pulmonary Disease

被引:2
|
作者
Bitar, Ahmad Naoras [1 ]
Khan, Amer Hayat [1 ]
Sulaiman, Syed Azhar Syed [1 ,2 ]
Ali, Irfhan Ali Bin Hyder [1 ,3 ]
Khan, Irfanullah [1 ]
机构
[1] Univ Sains Malaysia, Dept Clin Pharm, Gelugore 11800, Penang, Malaysia
[2] Univ Sains Malaysia Bertam, Adv Med & Dent Inst, Jln Tun Hamdan Sheikh Tahir, Kepala Batas 13200, Penang, Malaysia
[3] Penang Gen Hosp, Chest Dept, Georgetown 10990, Guyana
来源
关键词
Addiction; chronic obstructive pulmonary disease; emphysema; heroin; smoking; DRAGON; COPD;
D O I
10.4103/jpbs.jpbs_353_21
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Introduction: Little is known about the correlation between chronic obstructive pulmonary disease (COPD) and heroin smoking. Heroin smoking is a recent underinvestigated problem. The goal of this study is to study the impact of heroin smoking among COPD patients. Methods: This is a descriptive clinical study. A combination of self-reporting questionnaires and data extraction tools were used to collect information during baseline tests, interviews, and follow-ups. Patients' medical, clinical, and socioeconomic history were recorded. Participants were recruited using random sampling from multiple centers. Results: Out of 1034 COPD patients, heroin smokers represented the vast majority of addiction cases (n = 133). Heroin smokers were leaner than non-addicts (19.78 +/- 4.07 and 24.01 +/- 5.6, respectively). The most common type of comorbidities among heroin smokers was emphysema (27%). Both the forced expiratory volume (FEV (1))/forced vital capacity ratio and FEV1% predicted were lower among heroin smokers than non-addicts (52.79 +/- 12.71 and 48.54 +/- 14.38, respectively). The majority of heroin smokers (55%) had advanced COPD, and at least 15% of heroin smokers suffered from frequent respiratory failure. The mean +/- SD for COPD onset age among heroin smokers was 44.23 +/- 5.72, and it showed a statistically significant correlation (P < 0.001). Conclusion: Heroin smoking might be linked to the onset of COPD. Heroin smokers showed a significantrespiratory impairment compared to tobacco smokers of the same age group.
引用
收藏
页码:S1215 / S1223
页数:9
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