Kawasaki syndrome;
Kawasaki disease;
hospitalizations;
epidemiology;
children;
infants;
United States;
D O I:
10.1542/peds.112.3.495
中图分类号:
R72 [儿科学];
学科分类号:
100202 ;
摘要:
Objective. To estimate the incidence and describe the epidemiologic characteristics of Kawasaki syndrome (KS) among children in the United States. Methods. Hospital discharge records with a KS diagnosis among patients < 18 years of age were obtained from the 1997 and 2000 Kids' Inpatient Database and weighted to estimate the number and rate of KS-associated hospitalizations for the United States. Results. In 2000, similar to 4248 hospitalizations associated with KS occurred in the United States, and the median age of patients at admission was 2 years. Children < 5 years of age accounted for 3277 of these KS hospitalizations (77%) and had a KS hospitalization rate of 17.1 per 100 000 children. This rate was similar to the 1997 rate of 17.6 per 100 000 children. The KS hospitalization rate was significantly higher for infants < 1 year of age than for children 1 to 4 years of age (19.8 and 16.4 per 100 000 children, respectively). The rate of KS hospitalizations among children aged <5 years was highest among Asian and Pacific Islander children and was followed by the rate for black children (39.0 and 19.7 per 100 000 children, respectively). No deaths associated with KS were reported among hospitalized children. The median charge for a KS hospitalization was $ 7779 ( mean $ 10 725) and the total annual charges for KS hospitalizations in 2000 were approximately $ 35 million among children < 5 years of age. Conclusions. Among children < 5 years of age, the annual KS-associated hospitalization rates were similar for 1997 and 2000. The epidemiologic characteristics and hospitalization rates for KS at a national level were consistent with those reported from earlier studies, suggesting that the incidence for KS has not markedly changed in the United States during the past decade.
机构:
Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Natl Ctr Emerging & Zoonot Infect Dis, US Dept Hlth & Human Serv, Atlanta, GA 30333 USACtr Dis Control & Prevent, Div Viral & Rickettsial Dis, Natl Ctr Emerging & Zoonot Infect Dis, US Dept Hlth & Human Serv, Atlanta, GA 30333 USA
Holman, Robert C.
Belay, Ermias D.
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机构:
Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Natl Ctr Emerging & Zoonot Infect Dis, US Dept Hlth & Human Serv, Atlanta, GA 30333 USACtr Dis Control & Prevent, Div Viral & Rickettsial Dis, Natl Ctr Emerging & Zoonot Infect Dis, US Dept Hlth & Human Serv, Atlanta, GA 30333 USA
Belay, Ermias D.
Christensen, Krista Y.
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机构:
Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Natl Ctr Emerging & Zoonot Infect Dis, US Dept Hlth & Human Serv, Atlanta, GA 30333 USACtr Dis Control & Prevent, Div Viral & Rickettsial Dis, Natl Ctr Emerging & Zoonot Infect Dis, US Dept Hlth & Human Serv, Atlanta, GA 30333 USA
Christensen, Krista Y.
Folkema, Arianne M.
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机构:
Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Natl Ctr Emerging & Zoonot Infect Dis, US Dept Hlth & Human Serv, Atlanta, GA 30333 USACtr Dis Control & Prevent, Div Viral & Rickettsial Dis, Natl Ctr Emerging & Zoonot Infect Dis, US Dept Hlth & Human Serv, Atlanta, GA 30333 USA
Folkema, Arianne M.
Steiner, Claudia A.
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机构:
Ctr Delivery Org & Markets, Healthcare Cost & Utilizat Project, Agcy Healthcare Res & Qual, US Dept Hlth & Human Serv, Rockville, MD USACtr Dis Control & Prevent, Div Viral & Rickettsial Dis, Natl Ctr Emerging & Zoonot Infect Dis, US Dept Hlth & Human Serv, Atlanta, GA 30333 USA
Steiner, Claudia A.
Schonberger, Lawrence B.
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Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Natl Ctr Emerging & Zoonot Infect Dis, US Dept Hlth & Human Serv, Atlanta, GA 30333 USACtr Dis Control & Prevent, Div Viral & Rickettsial Dis, Natl Ctr Emerging & Zoonot Infect Dis, US Dept Hlth & Human Serv, Atlanta, GA 30333 USA
机构:
Natl Ctr Infect Dis, Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Atlanta, GA USANatl Ctr Infect Dis, Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Atlanta, GA USA
Belay, ED
Holman, RC
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机构:
Natl Ctr Infect Dis, Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Atlanta, GA USANatl Ctr Infect Dis, Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Atlanta, GA USA
Holman, RC
Shahriari, A
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Natl Ctr Infect Dis, Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Atlanta, GA USANatl Ctr Infect Dis, Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Atlanta, GA USA
Shahriari, A
Mandel, EJ
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Natl Ctr Infect Dis, Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Atlanta, GA USANatl Ctr Infect Dis, Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Atlanta, GA USA
Mandel, EJ
Schonberger, LB
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Natl Ctr Infect Dis, Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Atlanta, GA USANatl Ctr Infect Dis, Ctr Dis Control & Prevent, Div Viral & Rickettsial Dis, Atlanta, GA USA
机构:
Massachusetts Gen Hosp, Dept Emergency Med, 125 Nashua St,Suite 920, Boston, MA 02114 USA
Univ Tokyo, Dept Clin Epidemiol & Hlth Econ, Sch Publ Hlth, Tokyo, Japan
Univ Tokyo, Dept Pediat Surg, Grad Sch Med, Tokyo, JapanMassachusetts Gen Hosp, Dept Emergency Med, 125 Nashua St,Suite 920, Boston, MA 02114 USA
Fujiogi, Michimasa
Goto, Tadahiro
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h-index: 0
机构:
Univ Tokyo, Dept Clin Epidemiol & Hlth Econ, Sch Publ Hlth, Tokyo, Japan
Univ Fukui, Grad Sch Med Sci, Fukui, JapanMassachusetts Gen Hosp, Dept Emergency Med, 125 Nashua St,Suite 920, Boston, MA 02114 USA
Goto, Tadahiro
Yasunaga, Hideo
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机构:
Univ Tokyo, Dept Clin Epidemiol & Hlth Econ, Sch Publ Hlth, Tokyo, JapanMassachusetts Gen Hosp, Dept Emergency Med, 125 Nashua St,Suite 920, Boston, MA 02114 USA
Yasunaga, Hideo
Fujishiro, Jun
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h-index: 0
机构:
Univ Tokyo, Dept Pediat Surg, Grad Sch Med, Tokyo, JapanMassachusetts Gen Hosp, Dept Emergency Med, 125 Nashua St,Suite 920, Boston, MA 02114 USA
Fujishiro, Jun
Mansbach, Jonathan M.
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机构:
Harvard Univ, Dept Pediat, Boston Childrens Hosp, Boston, MA 02115 USA
Harvard Univ, Harvard Med Sch, Boston, MA 02115 USAMassachusetts Gen Hosp, Dept Emergency Med, 125 Nashua St,Suite 920, Boston, MA 02114 USA
Mansbach, Jonathan M.
Camargo, Carlos A., Jr.
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机构:
Massachusetts Gen Hosp, Dept Emergency Med, 125 Nashua St,Suite 920, Boston, MA 02114 USAMassachusetts Gen Hosp, Dept Emergency Med, 125 Nashua St,Suite 920, Boston, MA 02114 USA
Camargo, Carlos A., Jr.
Hasegawa, Kohei
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机构:
Massachusetts Gen Hosp, Dept Emergency Med, 125 Nashua St,Suite 920, Boston, MA 02114 USAMassachusetts Gen Hosp, Dept Emergency Med, 125 Nashua St,Suite 920, Boston, MA 02114 USA