How pre-B cells know when they have it right

被引：5
|
作者：
Schlissel, M [1 ]
机构：
[1] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA
来源：
NATURE IMMUNOLOGY | 2003年 / 4卷 / 09期
关键词：
D O I：
10.1038/ni0903-817
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Early B cell development faces a critical checkpoint at the pro-B --> pre-B transition stage, at which proper assembly and surface expression of an immunoglobulin heavy chain is somehow signaled by the pre-B cell receptor. Triggering of this signal might not require exogenous ligands.
引用
收藏
页码：817 / 819
页数：3
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