Playing Favorites: Integrin αvβ5 Mediates Preferential Zika Infection of Neural Stem Cells

被引:5
|
作者
Vazquez, Christine [1 ]
Jurado, Kellie Ann [1 ]
机构
[1] Univ Penn, Dept Microbiol, Philadelphia, PA 19104 USA
关键词
VIRUS;
D O I
10.1016/j.stem.2020.01.007
中图分类号
Q813 [细胞工程];
学科分类号
摘要
The molecular basis dictating specificity of Zika virus infection in neural stem cells (NSCs) remains elusive. Two recent papers in Cell Stem Cell (Zhu et al., 2020) and Cell Reports (Wang et al., 2020) identify integrin alpha v beta 5 as an internalization factor that increases susceptibility in NSCs and glioblastoma stem cells.
引用
收藏
页码:133 / 135
页数:4
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