Clopidogrel, Prasugrel, or Ticagrelor? A Practical Guide to Use of Antiplatelet Agents in Patients With Acute Coronary Syndromes

被引：18
|
作者：
Norgard, Nicholas B. [1 ]
DiNicolantonio, James J. [2 ]
机构：
[1] SUNY Buffalo, Pharm Practice UB Ctr Excellence, Sch Pharm & Pharmaceut Sci, Buffalo, NY 14260 USA
[2] Wegmans Pharm, Ithaca, NY USA
来源：
POSTGRADUATE MEDICINE | 2013年 / 125卷 / 04期
关键词：
clopidogrel; prasugrel; ticagrelor; aspirin; acute coronary syndromes; VASODILATOR-STIMULATED PHOSPHOPROTEIN; RESIDUAL PLATELET REACTIVITY; ASPIRIN-TREATED PATIENTS; COLLEGE-OF-CARDIOLOGY; ARTERY-BYPASS SURGERY; LOADING DOSE 300; MYOCARDIAL-INFARCTION; ACTIVE METABOLITE; COST-EFFECTIVENESS; CARDIOVASCULAR EVENTS;
D O I：
10.3810/pgm.2013.07.2682
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Aspirin is a cornerstone of therapy in the treatment of patients with acute coronary syndromes (ACS). However, dual antiplatelet therapy reduces the risk of stent thrombosis and cardiovascular events compared with aspirin alone in the treatment of patients with ACS. Recently, there has been debate as to which antiplatelet agent should be added to aspirin in the ACS treatment regimen. This review summarizes the pharmacologic and clinical data comparing clopidogrel, prasugrel, and ticagrelor, and provides a practical guide to clinicians for determining which antiplatelet to use for patients with ACS.
引用
收藏
页码：91 / 102
页数：12
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