Influence of water content on the ablation of skin with a 532 nm nanosecond Nd:YAG laser

被引:3
|
作者
Kim, Soogeun
Eom, Tae Joong
Jeong, Sungho
机构
[1] Gwangju Institute of Science and Technology, School of Mechatronics, 1 Oryong-dong Buk-gu, Gwangju
[2] Gwangju Institute of Science and Technology, Advanced Photonics Research Institute, 1 Oryong-dong Buk-gu, Gwangju
关键词
laser ablation; water content; tissue; skin; visible wavelength; SWITCHED ND-YAG; OPTICAL-PROPERTIES; SELECTIVE PHOTOTHERMOLYSIS; TRANSDERMAL DELIVERY; BIOLOGICAL TISSUES; PIGMENTED LESIONS; COLLAGEN-FIBERS; DENTAL ENAMEL; 8; WAVELENGTHS; IN-VITRO;
D O I
10.1117/1.JBO.20.1.018001
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
This work reports that the ablation volume and rate of porcine skin changed significantly with the change of skin water content. Under the same laser irradiation conditions (532 nm Nd:YAG laser, pulse width - 11.5 ns, pulse energy - 1.54 J, beam radius - 0.54 mm), the ablation volume dropped by a factor of 4 as the skin water content decreased from 40 wt. % (native) to 19 wt. % with a change in the ablation rate below and above around 25 wt. %. Based on the ablation characteristics observed by in situ shadowgraph images and the calculated tissue temperatures, it is considered that an explosive rupture by rapid volumetric vaporization of water is responsible for the ablation of the high water content of skin, whereas thermal disintegration of directly irradiated surface layer is responsible for the low water content of skin. (C) 2015 Society of Photo-Optical Instrumentation Engineers (SPIE)
引用
收藏
页数:10
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