Treatment options for methicillin-resistant Staphylococcus aureus (MRSA) infection: Where are we now?

被引:19
|
作者
Edwards, B. [1 ]
Andini, R. [2 ]
Esposito, S. [3 ]
Grossi, P. [4 ]
Lew, D. [5 ]
Mazzei, T. [6 ]
Novelli, A. [6 ]
Soriano, A. [7 ]
Gould, I. M. [8 ]
机构
[1] Royal Infirm Edinburgh NHS Trust, Dept Med Microbiol, Edinburgh EH16 4SA, Midlothian, Scotland
[2] Univ Naples 2, AORN Monaldi, UOC Transplant & Infect Dis Med, Naples, Italy
[3] Univ Salerno, Dept Med, I-84100 Salerno, Italy
[4] Univ Unisubria, Dept Surg & Morphol Studies, Varese, Italy
[5] Univ Hosp Geneva, Chief Dept Specialties Internal Med, Chief Infect Dis Div, Geneva, Switzerland
[6] Univ Florence, Dept Hlth Sci, Clin Pharmacol & Oncol Sect, Florence, Italy
[7] Hosp Clin Barcelona, IDIBAPS, Dept Infect Dis, Barcelona, Spain
[8] Aberdeen Royal Infirm, Dept Med Microbiol, Aberdeen, Scotland
关键词
MRSA; Treatment; Susceptibility testing; MINIMUM INHIBITORY CONCENTRATION; HIGH-DOSE DAPTOMYCIN; BLOOD-STREAM INFECTIONS; LINEZOLID-ASSOCIATED THROMBOCYTOPENIA; CONTINUOUS VENOVENOUS HEMOFILTRATION; VANCOMYCIN-INTERMEDIATE RESISTANCE; CRITICALLY-ILL PATIENTS; SOFT-TISSUE INFECTIONS; CONTINUOUS-INFUSION; EXPERIMENTAL ENDOCARDITIS;
D O I
10.1016/j.jgar.2014.03.009
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Methicillin-resistant Staphylococcus aureus (MRSA) infection continues to be a substantial global problem with significant associated morbidity and mortality. This review summarises the discussions that took place at the 4th MRSA Consensus Conference in relation to the current treatment options for serious MRSA infections and how to optimise whichever therapy is embarked upon. It highlights the many challenges faced by both the laboratory and clinicians in the diagnosis and treatment of MRSA infections. (C) 2014 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:133 / 140
页数:8
相关论文
共 50 条
  • [1] Methicillin-Resistant Staphylococcus aureus (MRSA) Infection
    Rod, Linda
    Hoyt, K. Sue
    [J]. ADVANCED EMERGENCY NURSING JOURNAL, 2007, 29 (02) : 118 - 128
  • [2] Methicillin-Resistant Staphylococcus aureus (MRSA): Review of Current Treatment Options in Pediatrics
    Purewal R.
    Lopez A.
    [J]. Current Treatment Options in Pediatrics, 2023, 9 (2) : 23 - 35
  • [3] Methicillin-Resistant Staphylococcus aureus (MRSA)
    Randolph, Susan A.
    [J]. WORKPLACE HEALTH & SAFETY, 2012, 60 (03) : 136 - 136
  • [4] Methicillin-resistant Staphylococcus aureus (MRSA) in Riyadh, Saudi Arabia: where do we stand?
    Baddour, MM
    Fatani, AJ
    AbuElKhair, MM
    Bohol, MF
    AlAhdal, MA
    [J]. PHARMACOTHERAPY, 2005, 25 (10): : 1459 - 1459
  • [5] METHICILLIN-RESISTANT STAPHYLOCOCCUS-AUREUS (MRSA)
    KEANE, CT
    [J]. IRISH MEDICAL JOURNAL, 1993, 86 (05) : 151 - &
  • [6] Methicillin-Resistant Staphylococcus Aureus (mrsa) In COPD
    Parameswaran, G. I.
    Sethi, S.
    Willet, A.
    Lesse, A.
    [J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2013, 187
  • [7] Methicillin-resistant Staphylococcus aureus (MRSA) in the Athlete
    Redziniak, D. E.
    Diduch, D. R.
    Turman, K.
    Hart, J.
    Grindstaff, T. L.
    MacKnight, J. M.
    Mistry, D. J.
    [J]. INTERNATIONAL JOURNAL OF SPORTS MEDICINE, 2009, 30 (08) : 557 - 562
  • [8] Methicillin-resistant Staphylococcus aureus (MRSA) - diagnostics
    Linde, H
    Lehn, N
    [J]. DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 2005, 130 (11) : 582 - 585
  • [9] MRSA: Methicillin-Resistant Staphylococcus aureus Foreword
    Leikin, Jerrold B.
    [J]. DM DISEASE-A-MONTH, 2008, 54 (12): : 750 - 750
  • [10] Innate defences against methicillin-resistant Staphylococcus aureus (MRSA) infection
    Komatsuzawa, H
    Ouhara, K
    Yamada, S
    Fujiwara, T
    Sayama, K
    Hashimoto, K
    Sugai, M
    [J]. JOURNAL OF PATHOLOGY, 2006, 208 (02): : 249 - 260