Thermal stability of haemoglobin solutions under DC and AC magnetic field and UV and IR radiation

被引：13
|
作者：
Drzazga, Z [1 ]
Michnik, A [1 ]
Bartoszek, M [1 ]
Beck, E [1 ]
机构：
[1] Silesian Univ, Inst Phys, Dept Med Phys, PL-40007 Katowice, Poland
来源：
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY | 2001年 / 65卷 / 02期
关键词：
DSC; electromagnetic field; haemoglobin; thermal stability;
D O I：
10.1023/A:1017910009660
中图分类号：
O414.1 [热力学];
学科分类号：
摘要：
The influence of electromagnetic field in wide range of frequency (extra low frequency magnetic field, monochromatic laser light 840 nm, ultraviolet light) and static magnetic field on the stability of aqueous and NaCl 0.9% haemoglobin solutions was studied using differential scanning calorimetry (DSC) method. Three steps of denaturation process can be derived from experimental data. The shifts of transition temperatures are more marked for NaCl 0.9% than for aqueous solutions. The results suggest that static magnetic field is effective in protecting protein, while ultraviolet radiation destabilises haemoglobin. The laser light and alternating magnetic field have a little effect on the thermal stability of haemoglobin.
引用
收藏
页码：575 / 582
页数：8
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