Intravascular delivery of hyperpolarized 129xenon for in vivo MRI

被引：11
|
作者：
Wolber, J [1 ]
Rowland, IJ [1 ]
Leach, MO [1 ]
Bifone, A [1 ]
机构：
[1] Royal Marsden NHS Trust, Joint Dept Phys, CRC, Clin Magnet Resonance Res Grp, Sutton SM2 5PT, Surrey, England
来源：
APPLIED MAGNETIC RESONANCE | 1998年 / 15卷 / 3-4期
关键词：
D O I：
10.1007/BF03162020
中图分类号：
O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号：
070203 ; 070304 ; 081704 ; 1406 ;
摘要：
The nuclear polarization of Xe-129 and He-3 can be enhanced by several orders of magnitude by using optical pumping techniques, thus allowing NMR detection of xenon and helium in very low concentrations. The benefits of optically enhanced magnetic resonance (MR) are already exploited in MR imaging of the lungs using optically polarized He-3. The high solubility of xenon in blood and lipids suggests a Variety of in vivo MR applications, for instance perfusion measurements or functional MR studies. This article reviews some current work directed towards delivery of optically polarized xenon for in vivo MR applications.
引用
收藏
页码：343 / 352
页数：10
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