Troponin levels in COVID-19 patients and its correlation with the severity of disease and clinical outcomes

Introduction: The epidemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) has become a major health problem globally. The most common cardiac manifestation of COVID-19 infection is acute cardiac injury observed in patients even without any prior cardiac comorbidities. It is seen that several patients positive for COVID-19 showed increased concentrations of cardiac troponin, which lead to confusion in clinical interpretation. Our study was performed to observe the correlation between elevated troponin levels with clinical outcomes and the severity of COVID-19 disease. Aim: To observe the correlation between elevated troponin levels with clinical outcomes and severity of COVID-19 disease. Materials and Methods: This was a cross-sectional study among 100 reverse transcription-polymerase chain reaction positive COVID-19 patients with measurement of troponin-I on the 1st and 5th days of admission. Results: The greatest number of deaths were reported in patients with troponin-I & GE; 0.39 ng/ml. Higher Troponin levels were seen in the elderly population. Higher Troponin Levels were also seen in severe diseases. Conclusion: The present study showed that higher troponin levels were associated with increased mortality in COVID-19 patients and higher values were observed with severe disease.