Dimensionality, responsiveness and standardization of the Bech-Rafaelsen Mania Scale in the ultra-short therapy with antipsychotics in patients with severe manic episodes

被引：30

作者：

Bech, P ^{[1
]}

Baastrup, PC

de Bleeker, E

Ropert, R

机构：

[1] Frederiksborg Cent Cty Hosp, Psychiat Res Unit, DK-3400 Hillerod, Denmark

[2] Copenhagen Univ Hosp, Dept Psychiat, Glostrup, Denmark

[3] Psychiat Hosp Glain, Univ Unit, St Lucia, Belgium

[4] Hosp Psychiat, St Lucia, Belgium

[5] Ctr Hosp St Anne, Paris, France

来源：

ACTA PSYCHIATRICA SCANDINAVICA | 2001年 / 104卷 / 01期

关键词：

psychiatric status rating scales; psychometrics; bipolar disorder; manic disorder; antipsychotics;

D O I：

10.1034/j.1600-0447.2001.00244.x

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Objective: Typical antipsychotics have their indication in the ultra-short (first week) treatment of severe episodes of mania. In this setting the Bech-Rafaelsen Mania Scale (MAS) was psychometrically compared with the Clinical Global Impression scale (CGI) to assess its ability to measure response. Method: Ratings on patients with marked to severe mania (n = 80) who participated in the clinical trials to evaluate the ultra-short antimanic effect of zuclopenthixol acetate were assessed. The MAS was analysed for internal validity (total score a sufficient statistic) and for external validity. Results: The MAS was shown to have a high internal validity showing onset of action already after days of treatment. After 6 days of treatment 53% of the patients responded according to the MAS but only 30% according to the CGI. The difference was statistically significant. Conclusion: The MAS has been found to be a valid scale to measure early onset of action and response in the ultra-short antimanic treatment with typical antipsychotics.

引用

页码：25 / 30

页数：6