Role of Inflammation in Psychiatric Disorders

被引：10

作者：

Jeon, Sang Won ^{[1
]}

Yoon, Ho-Kyoung ^{[2
]}

Kim, Yong-Ku ^{[2
]}

机构：

[1] Sungkyunkwan Univ, Sch Med, Dept Psychiat, Kangbuk Samsung Hosp, 29,Saemunan Ro, Seoul 03181, South Korea

[2] Korea Univ, Coll Med, Dept Psychiat, Ansan Hosp, 123,Jeokgeum Ro, Ansan 15355, Gyeonggi Do, South Korea

来源：

FRONTIERS IN PSYCHIATRY: ARTIFCIAL INTELLIGENCE, PRECISION MEDICINE, AND OTHER PARADIGM SHIFTS | 2019年 / 1192卷

关键词：

Inflammation; Neuroinflammation; Cytokine; Psychiatric disorder; Depression; Medication; MAJOR DEPRESSION; INTERFERON-ALPHA; DOUBLE-BLIND; CYTOKINES; BRAIN; NEUROINFLAMMATION; CURCUMIN; SYSTEM; ACTIVATION; PAROXETINE;

D O I：

10.1007/978-981-32-9721-0_24

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

Psychiatric disorders are too multifactorial to be defined as a primarily-inflammatory disorder, and increased inflammatory response is not specific to mental disorder only. Numerous factors are involved in neuroinflammation, and there also are many confounding variables, making it difficult to obtain-consistent outcomes. Therefore, it is necessary to specify genetic, physiological, and epidemiological attributes of particular population groups vulnerable to inflammatory response as well as the disease subtypes. As of now, definitive inflammatory markers for psychiatric disorders have not been identified, but they could be very useful in patients with minimal vulnerability. In addition, it is possible to use inflammatory markers as depression biomarkers in subtypes of depression, which can serve as bases to develop medications to treat the disorder.

引用

页码：491 / 501

页数：11

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