The clinical utility of gene expression assays in breast cancer patients with 0-3 involved lymph nodes

被引：6

作者：

Barbi, Mali ^{[2
]}

Makower, Della ^{[1
]}

Sparano, Joseph A. ^{[3
]}

机构：

[1] Montefiore Med Ctr, Dept Oncol, 1695 Eastchester Rd, Bronx, NY 10461 USA

[2] Montefiore Einstein Ctr Canc Care, Bronx, NY USA

[3] Mt Sinai Sch Med, Div Hematol Oncol, New York, NY USA

来源：

THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY | 2021年 / 13卷

关键词：

breast cancer; chemotherapy; gene expression profiling; hormone receptor-positive breast cancer; hormone therapy; 21-GENE RECURRENCE SCORE; ADJUVANT SYSTEMIC THERAPY; DISTANT RECURRENCE; POSTMENOPAUSAL PATIENTS; AMERICAN SOCIETY; GUIDE DECISIONS; PAM50; RISK; INDEX; PREDICTION; BENEFIT;

D O I：

10.1177/17588359211038467

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Multigene expression assays are prognostic for recurrence in hormone-receptor positive 2 (HER-2) negative breast cancer, and, in some cases, predictive of benefit from chemotherapy or extended endocrine therapy. The results of these assays may be used to guide treatment recommendations for early HER-2 negative breast cancer. We review the results of trials establishing the clinical utility of several commercially available gene expression assays.

引用

页数：14

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