Galanin message-associated peptide suppresses growth and the budded-to-hyphal-form transition of Candida albicans

被引：22
|
作者：
Rauch, Isabella
Lundstroem, Linda
Hell, Markus
Sperl, Wolfgang
Kofler, Barbara [1 ]
机构：
[1] Paracelsus Med Univ, Univ Hosp Salzburg, Dept Pediat, A-5020 Salzburg, Austria
[2] Stockholm Univ, Dept Neurochem, S-10691 Stockholm, Sweden
[3] Paracelsus Med Univ, Univ Hosp Salzburg, Dept Hosp Epidemiol & Infect Control, A-5020 Salzburg, Austria
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2007年 / 51卷 / 11期
关键词：
D O I：
10.1128/AAC.00166-07
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The expression of the mRNA encoding galanin message-associated peptide (GMAP) in human keratinocytes is upregulated by lipopolysaccharides and exposure to Candida albicans. GMAP has growth-inhibiting activity against C albicans and inhibits the budded-to-hyphal-form transition, establishing GMAP as a possible new component of the innate immune system.
引用
收藏
页码：4167 / 4170
页数：4
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