Transcatheter aortic valve replacement in patients with severe aortic stenosis and heart failure

被引：12
|
作者：
Bavishi, Chirag [1 ]
Kolte, Dhaval [1 ]
Gordon, Paul C. [1 ]
Abbott, J. Dawn [1 ]
机构：
[1] Brown Univ, Rhode Isl Hosp, Warren Alpert Med Sch, Dept Med,Div Cardiol, 593 Eddy St,RIH APC814, Providence, RI 02903 USA
来源：
HEART FAILURE REVIEWS | 2018年 / 23卷 / 06期
关键词：
Aortic stenosis; Valvular heart disease; Heart failure; LEFT-VENTRICULAR HYPERTROPHY; GLOBAL LONGITUDINAL STRAIN; LONG-TERM OUTCOMES; NATRIURETIC PEPTIDE; EJECTION FRACTION; MITRAL REGURGITATION; MYOCARDIAL DEFORMATION; SYSTOLIC DYSFUNCTION; MAGNETIC-RESONANCE; PROGNOSTIC VALUE;
D O I：
10.1007/s10741-018-9726-8
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Severe aortic stenosis (AS) and heart failure (HF) represent an important and high-risk group of patients who are often referred for transcatheter aortic valve replacement (TAVR) due to high risk for surgical intervention. Thus far, randomized controlled trials have shown comparable outcomes between TAVR and surgical aortic valve replacement in patients with severe AS and heart failure with reduced ejection fraction. In the current review, we will discuss (1) the pathophysiology of HF in patients with severe AS, (2) role of imaging modalities in management, (3) role of biomarkers of HF on prognosis, (4) impact of other valvular heart diseases, (5) evidence from the contemporary trials on the role of TAVR in patients with severe AS and HF, and (6) future directions and research.
引用
收藏
页码：821 / 829
页数：9
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