Red blood cell-derived microparticles: An overview

被引:53
|
作者
Westerman, Maxwell [1 ]
Porter, John B. [2 ]
机构
[1] Mt Sinai Hosp, 1500 South Calif Ave, Chicago, IL 60608 USA
[2] UCL, Dept Haematol, 72 Huntley St, London N1 4PZ, England
关键词
Red blood cell-derived microparticles; Overview; PROCOAGULANT ACTIVITY; ERYTHROCYTE VESICULATION; MEMBRANE SKELETON; LIPID-BILAYER; VESICLES; RELEASE; PHOSPHATIDYLSERINE; FRAGMENTATION; MICROVESICLES; MORPHOLOGY;
D O I
10.1016/j.bcmd.2016.04.003
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The red blood cell (RBC) is historically the original parent cell of microparticles (MPs). In this overview, we describe the discovery and the early history of red cell-derived microparticles (RMPs) and present an overview of the evolution of RMP. We report the formation, characteristics, effects of RMP and factors which may affect RMP evaluation. The review examines RMP derived from both normal and pathologic RBC. The pathologic RBC studies include sickle cell anemia (SCA), sickle cell trait (STr), thalassemia intermedia (TI), hereditary spherocytosis (HS), hereditary elliptocytosis (HE), hereditary stomatocytosis (HSt) and glucose-6-phosphate dehydrogenase deficiency (G6PD). (C) 2016 Elsevier Inc. All rights reserved.
引用
收藏
页码:134 / 139
页数:6
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