Safety and tolerance of palivizumab administration in a large Northern Hemisphere trial

被引：23
|
作者：
Groothius, JR [1 ]
机构：
[1] Abbott Int, No Hemisphere Expanded Access Study Grp, Abbott Pk, IL USA
来源：
PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2001年 / 20卷 / 06期
关键词：
respiratory syncytial virus; premature infants; monoclonal antibodies; bronchopulmonary dysplasia; chronic lung disease; respiratory disease; infectious disease;
D O I：
10.1097/00006454-200106000-00018
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
An Expanded Access Study was conducted to collect additional safety data on palivizumab. Pre-term infants with or without bronchopulmonary dysplasia received palivizumab every 30 days during the respiratory syncytial virus season. Adverse events were low (6.9%) in the 565 subjects. Serious adverse events included hospitalization and 1 case of respiratory syncytial virus bronchiolitis not requiring hospitalization. This study reaffirms the safety and tolerability of palivizumab.
引用
收藏
页码：628 / 630
页数：3
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