Focal segmental glomerulosclerosis associated with polycythemia vera: report of a case and review of the literature

被引：0
|
作者：
Okuyama, S. [1 ]
Hamai, K. [2 ]
Fujishima, M. [1 ]
Ohtani, H. [1 ]
Komatsuda, A. [1 ]
Sawada, K. [1 ]
Wakui, H. [1 ]
机构：
[1] Akita Univ, Sch Med, Dept Internal Med 3, Akita 0108543, Japan
[2] Nakadoori Gen Hosp, Akita, Japan
来源：
CLINICAL NEPHROLOGY | 2007年 / 68卷 / 06期
关键词：
focal segmental glomerulosclerosis; nephrotic syndrome; polycythemia vera;
D O I：
暂无
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
A 69-year-old female with a 3-year history of polycythemia vera (PV) developed nephrotic syndrome. A renal biopsy showed focal and segmental glomerulosclerosis (FSGS). The patient was treated with prednisolone and myelosuppressive agents. Thereafter, parallel improvement of the two conditions was observed. After 4-year treatment, proteinuria disappeared. To our knowledge, there are five reported cases of FSGS associated with PV Among them, three patients suffered from progressive azotemia. We suggest that steroid therapy with myelosuppressive agents can resolve the renal lesion in patients with PV.
引用
收藏
页码：412 / 415
页数：4
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