Effects of caffeine on cerebral blood flow

被引：0
|
作者：
Bláha, M [1 ]
Ostry, S [1 ]
机构：
[1] UVN, LF UK, Neurochirurg Klin 1, C-16902 Prague 6, Czech Republic
来源：
CESKA A SLOVENSKA NEUROLOGIE A NEUROCHIRURGIE | 2003年 / 66卷 / 05期
关键词：
caffeine; transcranial Doppler ultrasonography; cerebral blood flow; adenosine;
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Caffeine, the most widely used central nervous system stimulant, is ingested in coffee, tea, chocolate or some non-alcoholic drinks. The aim of this study was to investigate the effect of caffeine intake on cerebral blood flow (CBF) using transcranial Doppler ultrasonography. Twenty adult volunteers had their heart rate, blood pressure, end-tidal CO2, and cerebral blood flow velocities in both middle cerebral arteries measured before and 30 minutes after caffeine intake (300 mg). CBF decreased by 19.3 % from baseline. Cerebral blood flow corrected to et-CO2 = 40 mm Hg decreased 10 to 19.3 %. Caffeine is a potent cerebral vasoconstrictor due to its antagonism at adenosine receptors.
引用
收藏
页码：335 / 337
页数：3
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