An Algorithm of Multiple Sequence Alignment Based on Consensus Sequence Searched by Simulated Annealing and Star Alignment

被引:0
|
作者
Yao, Dengfeng [1 ,2 ]
Jiang, Minghu [2 ]
You, Xu [3 ]
Abulizi, Abudoukelimu [2 ]
Hou, Renkui [2 ,4 ]
机构
[1] Beijing Union Univ, Beijing Key Lab Informat Serv Engn, Beijing 100101, Peoples R China
[2] Tsinghua Univ, Sch Humanities, Lab Computat Linguist, Beijing 100084, Peoples R China
[3] Beijing Inst Petrochem Technol, Dept Math & Phys, Beijing 100084, Peoples R China
[4] Ludong Univ, Sch Literature, Yantai 264025, Shandong, Peoples R China
关键词
multiple sequence alignment; simulated annealing; consensus sequence; star alignment;
D O I
暂无
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Sequence alignment is an important method of sequence analysis in biological informatics, by which the characteristics of a gene family can be conveniently determined through consensus sequence. Finding a consensus sequence prior to multiple sequence alignment makes the sequence alignment easier. Thus, the consensus sequence should be produced by simulated annealing and star alignment algorithms. Furthermore, the star alignment can be used to compare each sequence in the consensus sequence.
引用
收藏
页码:3 / 6
页数:4
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