Impact of Preventive Measures on Subjective Symptoms and Antigen Sensitization against Japanese Cedar, Cypress Pollen and House Dust Mites in Patients with Allergic Rhinitis: A Retrospective Analysis in the COVID-19 Era

被引：1

作者：

Oda, Takashi ^{[1
]}

Maeda, Fumiaki ^{[1
]}

Takeno, Sachio ^{[1
]}

Tsuru, Yuri ^{[1
]}

Ishikawa, Chie ^{[1
]}

Ishino, Takashi ^{[1
]}

Takemoto, Kota ^{[1
]}

Hamamoto, Takao ^{[1
]}

Ueda, Tsutomu ^{[1
]}

Kawasumi, Tomohiro ^{[1
]}

Iwamoto, Hiroshi ^{[2
]}

Kubota, Kazunori ^{[3
]}

Nakao, Yoshio ^{[4
]}

Kunimoto, Masaru ^{[1
,5
]}

机构：

[1] Hiroshima Univ, Grad Sch Biomed Sci, Dept Otorhinolaryngol Head & Neck Surg, Hiroshima 7348551, Japan

[2] Hiroshima Univ, Grad Sch Biomed & Hlth Sci, Dept Mol & Internal Med, Hiroshima 7348551, Japan

[3] Kubota ENT & Allergy Clin, Hiroshima 7315141, Japan

[4] Nakao ENT & Allergy Clin, Hiroshima 7300823, Japan

[5] Kunimoto ENT Clin, Hiroshima 7313164, Japan

来源：

ATMOSPHERE | 2022年 / 13卷 / 07期

基金：

日本学术振兴会;

关键词：

allergic rhinitis; face mask; COVID-19; house dust mite; Japanese cedar pollen; Japanese cypress pollen; preventive behavior; subjective symptoms; NATURAL-HISTORY; STATE;

D O I：

10.3390/atmos13071000

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

For >2 years, Japan's government has been urging the populace to take countermeasures to prevent COVID-19, including mask wearing. We examined whether these preventive behaviors have affected the rate and degree of sensitization against pollen and house dust antigens in patients with allergic rhinitis. We retrospectively surveyed 2565 patients who had undergone allergy blood testing during the period 2015-2021. We subdivided this period into eras based on the COVID-19 pandemic: the pre-COVID (2015-2019, n = 1879) and COVID (2020-2021, n = 686) eras. The positive rates for Japanese cedar and cypress in the 40-59-year-olds and those for house dust in the 20-39-year-olds were significantly reduced in the COVID era versus those in the pre-COVID era. Each group's mean antigen-specific CAP scores decreased significantly from the 1st to 2nd era: from 1.98 to 1.57 for cedar (p < 0.01), 1.42 to 0.95 for cypress (p < 0.05), and 2.86 to 2.07 for house dust (p < 0.01). Our survey of the patients' clinical records indicates that 47.5% of the pollinosis patients reported improvement in nasal symptoms after the three seasons of pollen dispersion in the COVID era. Japan's quarantine policies designed to combat the spread of COVID-19 thus coincide with pivotal measures to alleviate allergic reactions.

引用

页数：10