Effect of White Matter Anisotropy in Modeling Electroconvulsive Therapy

被引:0
|
作者
Bai, Siwei [1 ]
Loo, Colleen [2 ]
Geng, Guangqiang [3 ]
Dokos, Socrates [1 ]
机构
[1] Univ New S Wales, Grad Sch Biomed Engn, Fac Engn, Sydney, NSW 2052, Australia
[2] UNSW, Sch Psychiat, Dept Psychiat, Sydney, NSW, Australia
[3] Neurosci Res, Sydney, NSW, Australia
关键词
BRAIN-TISSUE ANISOTROPY; DIFFUSION TENSOR MRI; EEG SOURCE ANALYSIS; MAGNETIC STIMULATION; HEAD MODEL; CONDUCTIVITY; COMPUTATION; IMPEDANCE; SKULL;
D O I
暂无
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
White matter in the brain exhibits strong anisotropic conductivity. Modeling studies on electroencephalography have found that such anisotropic conductivity greatly influences the estimated dipole source. In this study, we made a detailed comparison of the effects of conductivity anisotropy using a computational model of electroconvulsive therapy (ECT). The human head model was a high resolution finite element model generated from MRI scans, implemented with tissue heterogeneity and an excitable neural model incorporated in the brain. Results showed that anisotropy in conductivity had minimal effects on the location of the brain region that was maximally activated, but it had relatively large effects on deep brain structures.
引用
收藏
页码:5492 / 5495
页数:4
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