Treatment of Infections Due to Aspergillus terreus Species Complex

被引：25
|
作者：
Lass-Floerl, Cornelia [1 ]
机构：
[1] Med Univ Innsbruck, Div Hyg & Med Microbiol, Schopfstr 41, A-6020 Innsbruck, Austria
来源：
JOURNAL OF FUNGI | 2018年 / 4卷 / 03期
关键词：
Aspergillus terreus; amphotericin B; resistance; antifungal treatment; AMPHOTERICIN-B RESISTANCE; PULMONARY ASPERGILLOSIS; INVASIVE ASPERGILLOSIS; SUSCEPTIBILITY; EPIDEMIOLOGY; VORICONAZOLE; AUSTRIA; VALUES;
D O I：
10.3390/jof4030083
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The Aspergillus terreus species complex is found in a wide variety of habitats, and the spectrum of diseases caused covers allergic bronchopulmonary aspergillosis, Aspergillus bronchitis and/or tracheobronchitis, and invasive and disseminated aspergillosis. Invasive infections are a significant cause of morbidity and mortality mainly in patients with hematological malignancy. The section Terrei covers a total of 16 accepted species of which most are amphotericin B resistant. Triazoles are the preferred agents for treatment and prevention of invasive aspergillosis. Poor prognosis in patients with invasive A. terreus infections seems to be independent of anti-Aspergillus azole-based treatment.
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页数：9
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