Biotransformation of racemic diisophorone by Cephalosporium aphidicola and Neurospora crassa

被引：7
|
作者：
Kiran, I [1 ]
Akar, T
Gorgulu, A
Kazaz, C
机构：
[1] Osmangazi Univ, Dept Chem, TR-26480 Eskinsehir, Turkey
[2] Ataturk Univ, Dept Chem, TR-25240 Erzurum, Turkey
来源：
BIOTECHNOLOGY LETTERS | 2005年 / 27卷 / 14期
关键词：
Cephalosoporium aphidicola; diisophorone; hydroxylation; Neurospora crassa;
D O I：
10.1007/s10529-005-7868-y
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Racemic diisophorone (500 mg) was converted by Cephalosporium aphidicola and Neurospora crassa over 10 days at 25 degrees C to 8 beta-hydroxydiisophorone in yields of 10% (52 mg) and 20% (103 mg), respectively. The structure was established by IR, specific rotation, mass spectral, 1D and 2D-NMR studies.
引用
收藏
页码：1007 / 1010
页数：4
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