Glucose Biosensor Based on Screen-Printed Electrodes and Glucose Oxidase Layer Modified by MWCNT-NH2

被引：4
|
作者：
Rogaleva, N. [1 ]
Korpan, Y. [1 ]
Biloivan, O. [1 ]
机构：
[1] Natl Acad Sci Ukraine, Inst Mol Biol & Genet, UA-03680 Kiev 143, Ukraine
来源：
SENSOR LETTERS | 2011年 / 9卷 / 06期
关键词：
NH2-Modified Multi-Walled Carbon Nanotubes; Amperometric Biosensor; Glucose Oxidase; D-Glucose; CARBON NANOTUBES;
D O I：
10.1166/sl.2011.1765
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Glucose biosensor based on screen-printed electrodes and glucose oxidase (GO(x)) layer modified by aminated multi-walled carbon nanotubes (MWCNT-NH2) has been developed. The optimal membrane composition for enzyme immobilization by covalent binding in saturated GA vapors was determined as 0.1% of GO(x), 0.25% of MWCNT-NH2, 6.0% of bovine serum albumin (BSA), and 5.0% of glycerol. It has been shown that the integration of MWCNT-NH2 into GO(x) membrane is an effective approach to extend the linear dynamic range of glucose determination and to improve the biosensor sensitivity. However, analytical performances of the MWCNT-NH2 modified biosensor are restricted in terms of lowering its detection limit.
引用
收藏
页码：2356 / 2359
页数：4
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