Cortical thickness of the frontopolar area in typically developing children and adolescents

被引：93
|
作者：
O'Donnell, S
Noseworthy, MD
Levine, B
Dennis, M
机构：
[1] Hosp Sick Children, Brain & Behav Program, Toronto, ON M5G 1X8, Canada
[2] Univ Toronto, Inst Med Sci, Toronto, ON M5S 1A1, Canada
[3] McMaster Univ, Dept Radiol, Hamilton, ON, Canada
[4] McMaster Univ, Dept Med Phys, Hamilton, ON, Canada
[5] Univ Toronto, Dept Psychol, Toronto, ON M5S 1A1, Canada
[6] Univ Toronto, Dept Med Neurol, Toronto, ON, Canada
[7] Rotman Res Inst, Toronto, ON, Canada
[8] Univ Toronto, Dept Surg, Toronto, ON, Canada
来源：
NEUROIMAGE | 2005年 / 24卷 / 04期
关键词：
frontopolar cortex (FPC); cortical thickness; development; laterality; gender;
D O I：
10.1016/j.neuroimage.2004.10.014
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The development of the frontopolar cortex (FPC) through late childhood and adolescence was investigated using measures of cortical thickness. T-1-weighted structural MRIs from 35 typically developing participants aged 8-20 years were used to construct 3D models of the brain, from which cortical thickness was measured. There was a significant inverse association between age and cortical thickness, such that cortical thickness decreased as age increased between 8 and 20 years. There was no effect of Literality or gender on cortical thickness. (C) 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码：948 / 954
页数：7
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