Human metapneumovirus infection in Thai children

被引:24
|
作者
Thanasugarn, W
Samransamruajkit, R
Vanapongtipagorn, P
Prapphal, N
Van den Hoogen, B
Osterhaus, ADME
Poovorawan, Y [1 ]
机构
[1] Chulalongkorn Univ, Viral Hepatitis Res Unit, Bangkok 10330, Thailand
[2] Chulalongkorn Univ, Resp Unit, Dept Paediat, Bangkok 10330, Thailand
[3] Erasmus Med Ctr, Dept Virol, Rotterdam, Netherlands
关键词
D O I
10.1080/00365540310000094
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Human metapneumovirus (hMPV) associated with clinical respiratory tract infection (RTI) in children was first isolated in the Netherlands. Of 120 Thai paediatric patients with RTI examined, 5 cases (4.2%) showed detectable hMPV based on N-gene-specific RT-PCR. All of them were negative for hRSV infection. Aligning the sequences with a reference strain revealed some nucleotide differences, which necessitates future investigation to evaluate clinical significance and genotype variation.
引用
收藏
页码:754 / 756
页数:3
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