Vitiligo improvement in a patient with Ankylosing spondylitis treated with infliximab

被引：33
|
作者：
Simon, J. -Abraham [2 ]
Burgos-Vargas, Ruben [1 ]
机构：
[1] Univ Nacl Autonoma Mexico, Hosp Gen Mexico, Fac Med, Dept Rheumatol,Serv Reumatol, Mexico City 06726, DF, Mexico
[2] CEM Hosp, Dept Internal Med, IMSS, UMAE Yucatan,Med Res Ctr, Mexico City, DF, Mexico
来源：
DERMATOLOGY | 2008年 / 216卷 / 03期
关键词：
Ankylosing spondylitis; infliximab; vitiligo; treatment; anti-TNF;
D O I：
10.1159/000112932
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Ankylosing spondylitis (AS) is a disabling disease affecting the enthesis and joints of the spine and peripheral sites. Tumour necrosis factor alpha (TNF-alpha) is a proinflammatory mediator which plays a significant role in the pathogenesis of AS. Infliximab (a chimeric monoclonal antibody which blocks the activity of TNF-alpha) is one of the most effective therapies of AS thus far. Vitiligo is a depigmenting disorder of the skin of unknown aetiology affecting 0.5-1% of the population. Here we describe the effect of infliximab on vitiligo in a patient with AS. Copyright (c) 2008 S. Karger AG, Basel.
引用
收藏
页码：234 / 235
页数：2
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