Healthy adult vaccination: An urgent need to prevent hepatitis B in China

被引:19
|
作者
Qiu, Yan [1 ]
Ren, Jingjing [1 ]
Yao, Jun [2 ]
机构
[1] Zhejiang Univ, Sch Med, Affiliated Hosp 1, Gen Practice Dept, Hangzhou 310003, Zhejiang, Peoples R China
[2] Zhejiang Prov Ctr Dis Control & Prevent, Hangzhou, Zhejiang, Peoples R China
关键词
China; hepatitis B; healthy adults; immunization; prevalence; IMMUNOGENICITY; NONRESPONDERS; SAFETY;
D O I
10.1080/21645515.2015.1086519
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Prevalence of hepatitis B is still high among adults in China, athough the prevalence in children has decreased dramatically. Immunization against hepatitis B among adults is urgently required. Through analyzing the immunogenicity of different doses, schedules and booster immunization among adults, we recommend 10 or 20 mu g with a 0-1-6-month schedule or a 0-1-12-month schedule for migrant adults. For immunity failure, increasing the dose or covalent vaccine is suggested to provide protective antibodies. To enhance immunity among adults, hepatitis B vaccine should be included in health insurance.
引用
收藏
页码:773 / 778
页数:6
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