The future of molecular diagnostics for drug-resistant tuberculosis

被引：3
|
作者：
Heysell, Scott K. [1 ]
Houpt, Eric R. [1 ]
机构：
[1] Univ Virginia, Div Infect Dis & Int Hlth, Charlottesville, VA 22908 USA
来源：
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS | 2012年 / 12卷 / 04期
关键词：
extensively drug-resistant; molecular; multidrug-resistant; Mycobacterium tuberculosis; PCR; susceptibility testing; MULTICENTER LABORATORY VALIDATION; MYCOLIC ACID ANALYSIS; MYCOBACTERIUM-TUBERCULOSIS; MULTIDRUG-RESISTANT; MICROSCOPIC-OBSERVATION; RIFAMPIN RESISTANCE; CLINICAL SPECIMENS; ETHAMBUTOL RESISTANCE; ANTIMICROBIAL DRUGS; CLASSICAL; 2ND-LINE;
D O I：
10.1586/ERM.12.25
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
The last decade has seen significant advances in tuberculosis diagnostics and drug susceptibility testing (DST). During the same time period the prevalence of drug-resistant tuberculosis has increased and therefore it has become critical to understand DST for medications used to treat multidrug-resistant and extensively drug-resistant tuberculosis. This review describes recent molecular diagnostic advances for DST. Recommendations are provided for clinicians interpreting molecular DST and we describe potential opportunities for the field.
引用
收藏
页码：395 / 405
页数：11
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