Clonal Hematopoiesis Is Frequent and Associated with Inferior Survival Irrespective of Transplantation Strategy in Patients with Newly Diagnosed Multiple Myeloma

被引：0
|
作者：
Sperling, Adam S. [1 ]
Redd, Robert [2 ]
Gibson, Christopher J. [2 ]
Miller, Peter G. [2 ]
Corre, Jill [3 ]
Moreau, Philippe [4 ]
Neuberg, Donna S. [5 ]
Samur, Mehmet K. [6 ,7 ]
Ebert, Benjamin L. [2 ]
Avet-Loiseau, Herve [8 ]
Munshi, Nikhil C. [9 ]
机构：
[1] Dana Farber Canc Inst, Boston, MA 02115 USA
[2] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA 02115 USA
[3] IUCT Oncopole, Unite Genom Myelome, Toulouse, France
[4] Univ Nantes, INSERM UMR 892, CNRS UMR 6299, Nantes, France
[5] Dana Farber Canc Inst, Dept Data Sci, Boston, MA 02115 USA
[6] Harvard Med Sch, Dana Farber Canc Inst, Dept Med Oncol, LeBow Inst Myeloma Therapeut, Boston, MA 02115 USA
[7] Harvard Med Sch, Dana Farber Canc Inst, Dept Med Oncol, Jerome Lipper Multiple Myeloma Ctr, Boston, MA 02115 USA
[8] Univ Paul Sabatier, Toulouse, France
[9] Harvard Med Sch, Dana Farber Canc Inst, Boston, MA 02115 USA
来源：
BLOOD | 2021年 / 138卷
关键词：
D O I：
10.1182/blood-2021-148050
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
1127
引用
收藏
页数：5
相关论文
共 50 条
  • [1] Clinical Outcomes and Evolution of Clonal Hematopoiesis in Patients with Newly Diagnosed Multiple Myeloma
    Mouhieddine, Tarek H.
    Nzerem, Chidimma
    Redd, Robert
    Dunford, Andrew
    Leventhal, Matthew
    Sklavenitis-Pistofidis, Romanos
    Tahri, Sabrin
    El-Khoury, Habib
    Steensma, David P.
    Ebert, Benjamin L.
    Soiffer, Robert J.
    Keats, Jonathan J.
    Mehr, Shaadi
    Auclair, Daniel
    Ghobrial, Irene M.
    Sperling, Adam S.
    Stewart, Chip
    Getz, Gad
    [J]. CANCER RESEARCH COMMUNICATIONS, 2023, 3 (12): : 2560 - 2571
  • [2] Clonal Hematopoiesis Prevalence Increases throughout Treatment of Newly Diagnosed Multiple Myeloma Patients
    Mouhieddine, Tarek H.
    Nzerem, Chidimma
    Redd, Robert A.
    Dunford, Andrew
    Leventhal, Matthew Joseph
    Sklavenitis-Pistofidis, Romanos
    Tahri, Sabrin
    El-Khoury, Habib
    Steensma, David P.
    Ebert, Benjamin L.
    Soiffer, Robert J.
    Keats, Jonathan J.
    Mehr, Shaadi
    Auclair, Daniel
    Sperling, Adam S.
    Stewart, Chip
    Getz, Gad
    Ghobrial, Irene M.
    [J]. BLOOD, 2021, 138
  • [3] Failure to achieve early disease response is associated with inferior survival in patients with newly diagnosed multiple myeloma
    Chee, Adrian
    Low, Michael S.
    Vilcassim, Shahla
    Gregory, Gareth P.
    Gilbertson, Michael
    Ratnasingam, Sumita
    Grigoriadis, George
    Fedele, Pasquale L.
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2018, 182 (05) : 739 - 741
  • [4] Advances in maintenance strategy in newly diagnosed multiple myeloma patients eligible for autologous transplantation
    Wahab, Ahsan
    Rafae, Abdul
    Faisal, Muhammad Salman
    Mushtaq, Kamran
    Ehsan, Hamid
    Khakwani, Maria
    Ashraf, Afia
    Rehan, Tayyab
    Ahmed, Zahoor
    Shah, Zunairah
    Khan, Aslam
    Anwer, Faiz
    [J]. EXPERT REVIEW OF HEMATOLOGY, 2020, 13 (12) : 1333 - 1347
  • [5] Monocytosis at Diagnosis Is Associated with Decreased Overall Survival in Patients with Newly Diagnosed Multiple Myeloma
    Edwards, Camille V.
    Yildirim, Cenk
    Fillmore, Nathanael
    Munshi, Nikhil C.
    [J]. BLOOD, 2020, 136
  • [6] Clonal hematopoiesis in patients with multiple myeloma undergoing autologous stem cell transplantation
    Chitre, Sneha
    Stoelzel, Friedrich
    Cuthill, Kirsty
    Streetly, Mathew
    Graham, Charlotte
    Dill, Claudia
    Mohamedali, Azim
    Smith, Alexander
    Schetelig, Johannes
    Altmann, Heidi
    Bornhaeuser, Martin
    Mufti, Ghulam J.
    [J]. LEUKEMIA, 2018, 32 (09) : 2020 - 2024
  • [7] EARLY AUTOLOGOUS STEM CELL TRANSPLANTATION IMPROVES SURVIVAL IN NEWLY DIAGNOSED MULTIPLE MYELOMA PATIENTS
    Cavallo, F.
    Spencer, A.
    Gay, F.
    Hajek, R.
    Petrucci, M. T.
    Ben Yehuda, D.
    Carella, A. M.
    Vallone, L. M.
    Oliva, S.
    Petro, D.
    Crippa, C.
    Siniscalchi, A.
    Gilestro, M.
    Pour, L.
    Maracci, L.
    Pescosta, N.
    Liberati, M.
    Magarotto, V.
    Scudla, V.
    Benevolo, G.
    Pulini, S.
    Caravita, T.
    Hardan, I.
    Boccadoro, M.
    Palumbo, A.
    [J]. HAEMATOLOGICA, 2014, 99 : 520 - 520
  • [8] Clonal hematopoiesis in patients with multiple myeloma undergoing autologous stem cell transplantation
    Sneha Chitre
    Friedrich Stölzel
    Kirsty Cuthill
    Mathew Streetly
    Charlotte Graham
    Claudia Dill
    Azim Mohamedali
    Alexander Smith
    Johannes Schetelig
    Heidi Altmann
    Martin Bornhäuser
    Ghulam J. Mufti
    [J]. Leukemia, 2018, 32 : 2020 - 2024
  • [9] Clonal Hematopoiesis in patients with Multiple Myeloma undergoing Autologous Stem Cell Transplantation
    Chitre, S.
    Stoelzel, F.
    Cuthill, K.
    Streetly, M.
    Graham, C.
    Bornhauser, M.
    Mufti, G.
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2018, 181 : 101 - 102
  • [10] Young age and autologous stem cell transplantation are associated with improved survival in newly diagnosed multiple myeloma
    Bove, Virginia
    Garrido, David
    Riva, Eloisa
    [J]. HEMATOLOGY TRANSFUSION AND CELL THERAPY, 2021, 43 (03) : 295 - 302
12345