Review: Aptamers in microfluidic chips

被引：64
|
作者：
Xu, Yuanhong [1 ]
Yang, Xiurong [1 ]
Wang, Erkang [1 ]
机构：
[1] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Grad Sch, Changchun 130022, Jilin, Peoples R China
来源：
ANALYTICA CHIMICA ACTA | 2010年 / 683卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Aptamers; Microfluidic chips; Affinity; Microchip electrophoresis; SURFACE-PLASMON RESONANCE; MICROCHIP CAPILLARY-ELECTROPHORESIS; AFFINITY-CHROMATOGRAPHY; CANCER-CELLS; RNA APTAMER; MICROMAGNETIC SELECTION; PROTEIN INTERACTIONS; MAGNETIC BEADS; SYSTEM; SENSOR;
D O I：
10.1016/j.aca.2010.10.007
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
This review, covering reports published from 2002 to August 2010, shows how aptamers have made significant contributions in the improvements of microfluidic chips for affinity extraction, separations and detections. Furthermore, microfluidic chip methods for studying aptamer-target interactions and performing aptamer selections have also been summarized. Accordingly, research vacancies and future development trends in these areas are discussed. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码：12 / 20
页数：9
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