Recent advances in enantioseparation by capillary electrophoresis using antibiotics and polysaccharides as chiral selectors A review

This review gives an overview of the use of antibiotics and polysaccharides as chiral selectors in the field of enantioseparation by capillary electrophoresis (CE). Antibiotics and polysaccharides are two important types of chiral selectors in CE, and have been utilized successfully in enantioseparation of various compounds including pharmaceuticals, biochemicals, agrochemicals, fine chemicals, etc. In this review, recent advances covering literature published from January 2006 to April 2010 in chiral CE separation with antibiotics and polysaccharides are summarized. These developments focus on the introductions of new chiral selectors, investigations in different CE modes containing micellar electrokinetic chromatography and nonaqueous capillary electrophoresis, studies on separation mechanisms and improvements in separation methods.