The gut microbiome in obesity

被引:148
|
作者
Tseng, Ching-Hung [1 ]
Wu, Chun-Ying [2 ,3 ,4 ,5 ]
机构
[1] Germark Biotechnol Co Ltd, Taichung, Taiwan
[2] Taipei Vet Gen Hosp, Div Translat Res, 322,Sec 2,Shipai Rd, Taipei 11217, Taiwan
[3] Natl Yang Ming Univ, Inst Clin Med, Taipei, Taiwan
[4] Natl Yang Ming Univ, Inst Publ Hlth, Taipei, Taiwan
[5] China Med Univ, Coll Publ Hlth, Taichung, Taiwan
关键词
Gut microbiome; Gut microbiota; Obesity; CHAIN FATTY-ACIDS; PROTEIN-COUPLED RECEPTOR; WEIGHT-LOSS; INTESTINAL MICROBIOTA; BACTERIAL COMMUNITY; GASTRIC BYPASS; RIBOSOMAL-RNA; LACTOBACILLUS; INFLAMMATION; ANTIBIOTICS;
D O I
10.1016/j.jfma.2018.07.009
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Obesity is worldwide epidemic given its rapid growth in global prevalence. Among the risk factors contributing to obesity, human gut microbiome recently emerges with unprecedented intimacy in host metabolism and inflammation. With the advances in sequencing technology, more and more detailed understandings towards the intricate relationships linking gut microbiome and obesity have been continuously disclosed. Herein, we review studies resolving associations between gut microbiome and obesity, and then mechanistic studies tackling the roles played by gut microbes in obesogenic physiology. Copyright (C) 2018, Formosan Medical Association. Published by Elsevier Taiwan LLC.
引用
收藏
页码:S3 / S9
页数:7
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