Extraction of trans-resveratrol from red wine and optimization by response surface methodology

被引：20
|
作者：
Rabesiaka, Mihasina [1 ,3 ]
Rakotondramasy-Rabesiaka, Lovasoa [1 ]
Mabille, Isabelle [2 ]
Porte, Catherine [1 ]
Havet, Jean-Louis [1 ]
机构：
[1] Cnam, Lab Genie Proc Environm Energie & Sante, EA 21, F-75003 Paris, France
[2] ENSCP UPMC, Lab Genie Proc Plasmas & Traitements Surface, EA 3492, F-75005 Paris, France
[3] Univ Antananarivo, Lab Chim Minerale, Fac Sci, Antananarivo 101, Madagascar
来源：
SEPARATION AND PURIFICATION TECHNOLOGY | 2011年 / 81卷 / 01期
关键词：
Liquid-liquid extraction; Resveratrol; Optimization; Doehlert design; PHYTOALEXIN RESVERATROL; LIQUID-CHROMATOGRAPHY; STILBENE; INFECTION; CHLORIDE; MOUSE; PHASE; TIME;
D O I：
10.1016/j.seppur.2011.06.042
中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
The optimization of liquid-liquid extraction of resveratrol from wine by organic solvent was investigated using a Doehlert design. Preliminary experiments were conducted to choose the solvent used for the experimental design. Two parameters were analysed: the composition of the binary solvent mixture and the solution/solvent ratio. The best result was obtained by superimposing the isoresponses of selectivity and yield. The optimum operating conditions for extraction were: (i) a solvent mixture of cyclohexane/pentanol with a weight ratio of 40/60 and (ii) a solution/solvent ratio of 30/70. Under these conditions, the yield is above 95% for a selectivity of about 6.6 parts per thousand. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码：56 / 61
页数：6
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