Mucocutaneous ulcerations secondary to methotrexate

被引：0
|
作者：
Warner, Jennifer [1 ]
Brown, Alissa [2 ]
Whitmore, S. Elizabeth [1 ]
Cowan, David A. [1 ]
机构：
[1] Johns Hopkins Univ, Sch Med, Johns Hopkins Outpatient Ctr, Dept Dermatol, Baltimore, MD 21287 USA
[2] Univ Pittsburgh, Dept Pediat, Pittsburgh, PA 15260 USA
来源：
CUTIS | 2008年 / 81卷 / 05期
关键词：
D O I：
暂无
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Although methotrexate (MTX) is used in several medical specialties including dermatology, rheumatology, and oncology, drug-induced mucocuta-. neous ulcerations rarely are reported. We present a 36-year-old woman with plaque psoriasis and psoriatic arthritis being treated with oral MTX (12.5 mg weekly) and oral methoxsalen plus UVA. Following an increase in MTX dose, she developed erosions and ulcerations on her oral mucosa and within her psoriatic plaques. All erosions and ulcerations healed within 2 weeks upon discontinuation of MTX.
引用
收藏
页码：413 / 416
页数：4
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